DESCOVY for PrEP?
- It is not for use in people assigned female at birth who are at risk of getting HIV from vaginal sex, because its effectiveness has not been studied.
- You must be
HIV-negativebefore and while taking DESCOVY for PrEP.
In the DISCOVER trial, 1% of people on DESCOVY for PrEP stopped
taking it because of side effects, compared to 2% of people taking TRUVADA®* for at least 2 years (~96 weeks)
PrEP medications are most effective when you take them every day. So it's important to find one that works for you. Ask your healthcare provider any questions you have about PrEP medications.
Common side effects for DESCOVY
|The results were analyzed when everyone had been in the study for at least 2 years (~96 weeks). At that point, common side effects† included:
*TRUVADA (emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg) tablets.
†Common side effects include any reported in 2% or more of study participants taking
‡Stomach discomfort can mean abdominal or gastrointestinal pain or discomfort.
DESCOVY can cause serious side effects:
Worsening of hepatitis B (HBV) infection. Your healthcare provider will test you for HBV. If you have HBV and stop taking DESCOVY, your HBV may suddenly get worse. Do not stop taking DESCOVY without first talking to your healthcare provider, as they will need to check your health or give you HBV medicine.
What are the other possible side effects of
DESCOVY for PrEP?
Serious side effects of DESCOVY may also include:
Kidney problems, including kidney failure. Your healthcare provider should do blood and urine tests to check your kidneys before and during treatment with DESCOVY. If you develop kidney problems, your healthcare provider may tell you to stop taking DESCOVY.
Too much lactic acid in your blood (lactic acidosis), which is a serious but rare medical emergency that can lead to death. Tell your healthcare provider right away if you get these symptoms: weakness or being more tired than usual, unusual muscle pain, being short of breath or fast breathing, stomach pain with nausea and vomiting, cold or blue hands and feet, feel dizzy or lightheaded, or a fast or abnormal heartbeat.
Severe liver problems, which in rare cases can lead to death. Tell your healthcare provider right away if you get these symptoms: skin or the white part of your eyes turns yellow, dark “tea-colored” urine, light-colored stools, loss of appetite for several days or longer, nausea, or stomach-area pain.
You are encouraged to report negative side
effects of prescription drugs to the FDA. Visit
www.FDA.gov/medwatch, or call